Talking Biotech · episode 417
The Pawpaw: History and Genetic Improvement - Adam D'Angelo
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Talking Biotech · episode 416
In The News: Citrus Greening Disease Update; Dangerous Seed Oils? Cameron English
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Talking Biotech · episode 415
Dogmatism Meets Unpopular Evidence: the Case of Second-Hand Smoke - Dr. Geoffrey Kabat
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Talking Biotech · episode 414
A Non-Profit Biotech Model; Therapies for Rare Diseases - Dr. Ashley Winslow
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Talking Biotech · episode 413
Understanding Your Genetics with 23andMe - Dr. Joyce Tung
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Talking Biotech · episode 412
Biotechnology in the Crime Lab - Brian Hoey
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Talking Biotech · episode 411
The Shill Accusation and How to Respond - Dr. Chris MacDonald
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Talking Biotech · episode 410
Sustainable Chemistry through Synthetic Biology - Dr. Chance Elliott, Amyris
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Talking Biotech · episode 409
A Look at the Color of Future Medical Care - Dr. Alicia Zhou
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Talking Biotech · episode 408
Breaking Barriers in Protein Therapeutics - Dr. Dan Mandell
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Talking Biotech · episode 407
Innovations in High Throughput Proteomics - Dr. Parag Malik
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Talking Biotech · episode 406
The Amazing Potential of Cell Transplants - Brian Culley
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Talking Biotech · episode 405
Adjusting to the Changing Biotech Landscape - Dr. Mike Tarselli
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Talking Biotech · episode 404
Drug Discovery in a Simulated Cell - Dr. Daniel Veres
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Talking Biotech · episode 403
COVID19 Misinformation "We Want Them Infected" - Dr. Jonathan Howard
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Talking Biotech · episode 402
Rebuttal to RFKj's Glyphosate Comments on Joe Rogan
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Talking Biotech · episode 401
Happy Green Guacamole - The Non-Browning Avocado. Dr. Jeff Touchman
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Talking Biotech · episode 400
Talking Biotech Past, Present and Future
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Talking Biotech · episode 399
Next Generation Livestock Vaccines - Joel Harris
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Talking Biotech · episode 398
Telling Science's Story - Sam Kean
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Talking Biotech · episode 397
Constructing Brain Maps with Machine Learning - Dr. Stephan Doyen
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Talking Biotech · episode 396
Novel Solutions for Chronic Kidney Disease -Dr. Andrew King
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Talking Biotech · episode 395
395 Synthetic Circuits in Plant Biology - Dr. James Lloyd
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Talking Biotech · episode 394
The Uphill Battle Against Scientific Disinformation - Dr. Lonni Besançon
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Talking Biotech · episode 393
How AI Has Changed the Business of Drug Discovery - Dr. Michael Zaizac
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Talking Biotech · episode 392
Renewing This Old Brain - Dr. Jean Hebert
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Talking Biotech · episode 391
Countering Livestock mRNA Vaccine Disinformation - Drs. Alison Van Eenennaam and Terry Lehenbauer
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Talking Biotech · episode 390
The Changing Biotech Business and Big Data Ecosystem - Dr. Jeffrey Reid, Regeneron
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Talking Biotech · episode 389
Science Controversies in Social Media - Dr. Liza Dunn
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Talking Biotech · episode 388
Biotech Potatoes and Food Security - Dr. David Douches
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Talking Biotech · episode 387
387 Students Against Misinformation -Special Epidsode-
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Talking Biotech · episode 386
Treating Mental Illness through Nasal Drug Delivery - Shawn Singh
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Talking Biotech · episode 385
Reinventing Lipid Nanoparticles - Dr. John Lewis
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Talking Biotech · episode 384
Gene Therapy to Cure Rare Disease - Dr. Gaurav Shah
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Talking Biotech · episode 383
Inspiring Innovations; State of Alzheirmer's Therapies
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Talking Biotech · episode 382
Nature's transgenics: Evidence of lateral gene transfer in plants with Dr. Lara Pereira
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Talking Biotech · episode 381
Status of the Biotech Salmon - Silvia Wulf
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Talking Biotech · episode 380
Stopping Long-Term Disease by Arresting Aging - Dr. Eric Morgen
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Aging is a normal developmental program that involves discrete expression of specific genes leading to particular physiological changes.
Talking Biotech · episode 379
The Risks of Manufactured Viruses - Dr. Kevin Esvelt
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Can biotechnology be used in malevolent ways? The simple and inexpensive ways to generate genetic material make creating viruses easier than ever.
Talking Biotech · episode 378
Biotech Fetal Diagnostics - Daniel Weisman
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How is biotechnology used to make predictions about fetal health conditions? Modern techniques can analyze DNA without invasive sampling, and a lot may be learned about fetal health from a mother's blood test.
Talking Biotech · episode 377
Brexit May Bring Gene Editing to the UK- Cameron English
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Brexit saw the UK step away from the European Union, with many economics and social repercussions. However, this change also brings scientific benefit, as the UK no longer has to function under the EU's regressive scientific regulatory hand.
Talking Biotech · episode 376
Releasing the Biotech Blight Resistant Chestnut - Erik Carlson
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The American chestnut was a dominant tree in many of the forests of the eastern United States. In the early 20th century an imported fungus spread quickly through the population, destroying trees across the range.
Talking Biotech · episode 375
New Cancer Drugs: Breaking the Cell Cycle -- Spiro Rombotis
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The cell cycle is a coordinated series of steps that cells follow during replication. Defects in cancer cells target or override these chemical constraints in proliferation.
Talking Biotech · episode 374
374 Bioengineering Yeast for Better Beer - Dr. Charles Denby
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Beer is a beverage derived from the interplay of chemistry within hops and grains, fermented by brewer's yeast.
Talking Biotech · episode 373
Genes Controlling Plant Size
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Plant stature is a surprisingly important trait. Growing short has its advantages, so understanding the genetic controls is important.
Talking Biotech · episode 372
As Gods: A Moral History of the Genetic Age - Matthew Cobb
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Just because we can, does it mean that we should? Technology is developing so fast and enables so many new opportunities, but is there reason to occasionally pause and consider broader implications? Prof.
Talking Biotech · episode 371
The Genomes of Parasites - Dr. Jessie Kissinger
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Parasites are a massive threat to human and animal health, underlying a significant number of important diseases.
Talking Biotech · episode 370
Cancer Misinformation - Dr. Skyler Johnson
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As lifespan increases due to prevention and treatment of infectious disease and heart disorders, long-term issues like cancer become more prevalent.
Talking Biotech · episode 369
Livestock, Climate Change, and Attacks on a Scientist - Dr. Frank Mitloehner
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Dr. Frank Mitloener is an expert in the contributions of livestock to climate change. He is a researcher that studies ways to mitigate the greenhouse gases from ruminant digestion, and a trusted expert in outreach to ensure the implementation of new strategies.
Talking Biotech · episode 368
A Gene-Edited Vaccine Against Malaria - Dr. Stefan Kappe
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Malaria is a deadly, mosquito-vectored disease in areas of the Developing World. Intensive efforts have resulted in few effective prophylactic or therapeutic practices or products that are without serious limitations.
Talking Biotech · episode 367
Seralini's Lumpy Rats - Ten Years Later
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Ten years ago a scientific paper claimed definitive evidence linking genetic engineering to tumors. The study by Giles-Eric Seralini and his team at CRIIGEN stunned the world, and it was amplified through social and traditional media.
Talking Biotech · episode 366
New Therapeutics for Novel Problems through Collaboration - Dr. Betsy O'neill
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How can collaboration bring new technology to those that need it, faster? Dr. Linda O'Neill, VP of External Innovation at Horizon Therapeutics describes how strategic partnerships can speed the development and deployment of new therapeutics, particularly for autoimmune disorders and potential treatments for rare disease.
Talking Biotech · episode 365
The Long COVID HERV Connection - Dr. Claudia Matteucci
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Human endogenous retroviruses (HERVs) are ancient viruses found in our genomes, remnants of long-past infections.
Talking Biotech · episode 364
Purple Tomatoes and Health - Dr. Cathie Martin
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The purple compounds in fruits and vegetables associate with the perception of health and flavor. Prof.
Talking Biotech · episode 363
Rapid Detection of Sexually Transmitted Infections with Microfluidics - Dr. Anna Dixon
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Sexually transmitted infections, once thought to be low frequency events, are staging a comeback. Dr.
Talking Biotech · episode 362
The Gut-Brain Axis: What it is, associated problems and new therapies. Nancy Thornberry
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Research is showing a more intimate association between the digestive system and the brain, a bi-directional sensing and signaling network that directs digestive physiology.
Talking Biotech · episode 361
Precision Insect Control with Gene Editing
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Insects inflict tremendous human casualty and massive losses in agriculture. For more than half a century Sterile Insect Technique has been implemented to crash invasive or dangerous populations by damaging insect genetics and releasing them into target populations.
Talking Biotech · episode 360
Update on Animal Gene Editing
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Amazing innovations in animal gene editing have the promise to streamline agriculture, with benefits for agricultural producers, consumers and the environment.
Talking Biotech · episode 359
Creating Targeted Antibodies in Single Cells
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Antibodies are one line of adaptive immune response, responding to new antigens that may represent threats.
Talking Biotech · episode 358
Extending Health and Life, Starting with Dogs
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Dogs are an excellent model to study the genetics and mechanisms of aging. Loyal CEO Celine Halioua describes how genetic variation between breeds leads to specific effects on lifespan and "healthspan", and how new therapeutics might enrich and extend their lives.
Talking Biotech · episode 357
Optimizing Animal Microbiomes
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The microbiome is a population of bacteria, fungi, protists and viruses that inhabit a specific environment.
Talking Biotech · episode 356
Glyphosate in Breast Milk? Eco-Modernism
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This episode has two parts. In the first part lactation specialist Dr. Shelley McGuire discusses the new paper that claims to have found glyphosate in breast milk.
Talking Biotech · episode 355
Stool-Based Detection of Colon Cancer
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Colorectal cancer is one of the most deadly cancers in the industrialized world. However, dangerous malignancies occur after multiple committed genetic steps at the cellular level that happen over years.
Talking Biotech · episode 354
Microalgae: Factories for Improved Polymers
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Modern life has benefitted from the development of polymers that can be fashioned into everything from car parts, to children's toys, to medical devices.
Talking Biotech · episode 353
CAR-T Therapies to Reverse Cardiac Fibrosis
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Injury to heart tissue results in non-functional scar tissue that compromises cardiac function. A new approach combines targeted lipid nanoparicles and mRNAs to reprogram immune cells to seek and destroy the pathogenic fibroblasts that limit heart function.
Talking Biotech · episode 352
352 - Prions and Chronic Wasting Disease
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Chronic wasting disease is an increasingly common prion-based disease of deer and other cervids. Dr. Sandra Pritzkow describes the disease, it's transmission, and efforts to mitigate its spread.
Talking Biotech · episode 351
351 - Biotech, Pesticides, Toxicology and Food
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There is abundant conversation about pesticides and food, especially in social media. Unfortunately, there is little understanding about regulation, dosage, tolerances and toxicity.
Talking Biotech · episode 350
Methylation of DNA, Relationship to Disease
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Methylation is the addition of a small methyl group to specific bases of the DNA helix. Addition of a methyl group can change how the DNA blueprint is accessed and expressed.
Talking Biotech · episode 349
Addressing the Issue of Scientific Reproducibility
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Trust in science is predicated on independent reproducibility of research results. Perceived breakdowns in reproducibility have gained much recent attention, and it is up to the scientific community to devise new mechanisms to help ensure methods and results are complete and transparent.
Talking Biotech · episode 348
The Human Protein Atlas
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Proteins are the central catalytic and structural components of cells, and ultimately are at the center of cellular function.
Talking Biotech · episode 347
New Drugs that Repair Broken Genes
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Many diseases do not have cures, yet have a foundation in deleterious genomic mutations. Dietrich Stephan of NewBase describes a novel custom drug design platform that shows amazing potential in animal models, and seeks to directly reverse currently untreatable disease.
Talking Biotech · episode 346
An Owner's Manual for Your Brain
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In the age of an internet full of false information, how do we tell the real from the fictitious? Jon Guy introduces his new book, Thinking Straight- an owner's manual to the mind.
Talking Biotech · episode 345
Update on Self-Limiting Mosquitoes
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Mosquitoes are the world's most deadly insect, vectoring dozens of bloodborne diseases. Oxitec has been revising "sterile insect" techniques classically used in mosquito control with modern technologies that are more precise.
Talking Biotech · episode 344
New Drugs Targeting Dangerous Cholesterol
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Specific modifications of cholesterol appear to be central in heart disease, stroke and other disorders.
Talking Biotech · episode 343
Breeding the Next Amazing Apple
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Apples are a fruit favorite. What are modern breeders doing to create the next generation of superior fruits, that offer flavors for consumers and sustainability traits for farmers? Dr.
Talking Biotech · episode 342
Biological Plasticity, Bioelectricity, and Limb Regeneration
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Dr. Michael Levin of Tufts University discusses his laboratory's eclectic research programs that may be changing the way we think about animal development.
Talking Biotech · episode 341
Consumer Sentiment and Gene Editing
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Scientists say that gene editing will have profound positive impacts in medicine and agriculture. But what do consumers think? Today's Talking Biotech Podcast talks to agricultural economist Dr.
Talking Biotech · episode 340
Stopping Bleeding with Algal-Based Polymers
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Catastrophic bleeding is a cause of death after a wide variety of wounds in humans and other animals.
Talking Biotech · episode 339
Fungal Toxins in Food
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Mother Nature has created some of the world's most carcinogenic compounds. These natural fungal products are present on many commodity crops, and have profound impacts in the developing nations.
Talking Biotech · episode 338
Plastics and Fuels from Camelina
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Camelina is a mustard-family plant that may be genetically engineered to create a wide variety of important products, from plastics to jet fuel.
Talking Biotech · episode 337
Endogenous Retroviruses and Disease, Dr. Arvinda Nath
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Our genomes carry a massive amount of integrated viral DNA from infections in our ancestors. New evidence shows that they may be reactivated and drive cancer and neurological disorders.
Talking Biotech · episode 336
Evaluating Scientific Claims - Melanie Trecek-King
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The world's information is available to us at our fingertips. How do we recognize good sources and evaluate scientific claims? Melanie Trecek-King describes her tool kit for critical thinking.
Talking Biotech · episode 335
Resetting the Table with Dr. Robert Paarlberg
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Dr. Robert Paarlberg discusses his book, "Resetting the Table - Straight Talk About the Food We Grow and Eat".
Talking Biotech · episode 334
Biotech and Tick Vectored Disease
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Ticks are important disease vectors, spreading Lyme Disease and other human pathogens. New technology permits improved functional genetic research as well as creates a basis for genetic engineering strategies to limit populations or control disease vectoring.
Talking Biotech · episode 333
Plant Viruses / X Files Science
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Dr. Anne Simon describes viral threats to plant biology, and discusses how scientists have harnessed viruses to solve problems in agriculture.
Talking Biotech · episode 332
New Therapies for HERV-Based Disease
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Expression from Human Endogenous Retroviruses (HERVs) has been liked to Multiple Sclerosis and Amyotrophic Lateral Sclerosis (ALS) and other neurological diseases.
Talking Biotech · episode 331
Talking Biotech Podcast Changes and Future
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New sponsorship will improve the listener experience. Here are some of the changes you'll see with this opportunity.
Talking Biotech · episode 330
Avocado Genetics and Improvement
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The avocado is a nutritious and delicious fruit. Today's episode discusses its history, domestication, breeding priorities and future.
Talking Biotech · episode 329
Hollywood and the Percy Schmeiser Story
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The story of Percy Schmeiser is a well known tale of big biotech against the little farmer from rural Saskatchewan.
Talking Biotech · episode 328
The Importance of Telling Ag’s Story
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One of the criticisms of farmers is that they fail to engage the public to show what they do. It is understandable, their days are busy, competition is stiff, and farming selects for folks that shun the spotlight.
Talking Biotech · episode 327
Attacking Disease by Targeting Proteins
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Many diseases are rooted in the incorrect accumulation of proteins that regulate key cellular processes.
Talking Biotech · episode 326
Update on Transgenic (“GMO”) Chestnut
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The American Chestnut used to dominate Appalachian forests, but declined after a fungal disease was introduced to North America in the early 1900’s.
Talking Biotech · episode 325
Is Biotechnology Just New Colonialism?
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Two unusually parallel articles emerged this week, both claiming that modern ag technology (as they say, “GMO”) is just another arm of colonial control of the Developing World.
Talking Biotech · episode 324
Wine Flavor: Merging Grape and Yeast Genomes
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Wine is a fermented beverage that has been enjoyed for millennia. While many may feel that the grapes used produce the flavors in the wine, a substantial contribution comes from the yeast and specialized bacteria that performs feats of biochemistry on the components lent by the grape itself.
Talking Biotech · episode 323
Cindy’s Gift to End Glioblastoma
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At the early age of 47 Cindy Lee Graham lost her battle with glioblastoma. Glioblastoma is an insidious cancer of the brain and central nervous system that slowly robs its victims of critical faculties, with a very low survival rate.
Talking Biotech · episode 322
Gender Equity in the Pharmaceutical Industry
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The executive ranks of the pharmaceutical industry are populated with a clear over representation of older males.
Talking Biotech · episode 321
The Challenges of Growing Plants in Space
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Sustained space travel and colonization will depend on the ability to grow food in extra-terrestrial environments.
Talking Biotech · episode 320
Tiredness: Time for DNA Repair!
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We all know the feeling of tiredness, but what causes the urge to sleep? Prof. Lior Appelbaum discusses the link between sleepiness and DNA damage, as sensed through the accumulation of a protein known as PARP1.
Talking Biotech · episode 319
Reprogramming T-Cells for Immunotherapies
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T Cells are the body’snatural defenders against pathogens. In the past they have been reprogrammed to recognize specific surface antigens of cancer cells to attack and destroy them.
Talking Biotech · episode 318
Breeding Future Olives
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Olives have a prominent role in the production of aromatic healthy culinary oils and brined olives for the table.